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Arthur Kornberg

Picture of Arthur Kornberg

Date of Birth: 03/03/1918

Age: 89

Place of birth: New York

Citizenship: United States

Background

He graduated from the City College of New York and the University of Rochester. In 1942, he was an officer in the Medical Service of the US Coast Guard. In 1942-1952 he worked at the National Institutes of Health in Bethesda, in 1947 during the year - in the School of Medicine of New York University as a visiting researcher in laboratoriiOchoa. From 1953 to 1959 - head of the microbiology department of George Washington University in St. Louis (pc Montana.), From 1959 - Professor, Department of Biochemistry, Stanford University, until 1969 - Dean of the Faculty.

The first work Kornberg devoted intermediates and metabolic enzymes involved in their education. These studies led to the discovery of chemical reactions responsible for the synthesis of flavin adenine dinucleotide and difosfouridinnukleotida - co-enzymes involved in redox processes in the cell. Investigating the mechanism of the synthesis of nucleotides - the monomeric units of DNA and RNA - Kornberg came to the problem of their connection with each other (polymerization). I isolate and purify the enzyme, now called DNA polymerase, which catalyzes the copying (replication) of DNA during cell division. Using as a template the natural DNA Kornberg first realized functionally active DNA synthesis in vitro.